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Fourleaf Milkweed (Asclepias quadrifolia Jacq.)

Also known as four-leaved milkweed.

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A perennial milkweed named for its distinctive growth-habit with whorls of four leaves around the stem.

Range - Expand

Native or Not Present

This tentative map is based on our own research. It may have limited data on Canada and/or Mexico, and there is some subjectivity in our assignment of plants as introduced vs. expanded. Read more in this blog post.


Common in dry, open rocky forests in upland areas, particularly on slopes. Common in, but generally restricted to these habitats. Can be found along roadsides and woodland edges in these habitats. Tolerant of drought and some shade, but intolerant of wet soils.


Uncommonly grown in gardens. Easy to grow on well-drained sites, but difficult to transplant.

Asclepias quadrifolia (Fourleaf Milkweed) | USDA PLANTS Database (About This Site)

Asclepias quadrifolia | Go Botany (About This Site)

Asclepias quadrifolia (Fourleaf Milkweed) | Missouri Botanical Garden Plant Finder (About This Site)

Asclepias quadrifolia | Biota of North America Project (BONAP) (About This Site)

Asclepias quadrifolia | NatureServe Explorer (About This Site)

Asclepias quadrifolia | Missouri Plants (About This Site)

Four-leaved Milkweed | Maryland Biodiversity Project (About This Site)